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Where is river blindness most common? Onchocerciasis is locally transmitted in 30 countries of Africa and in Yemen in the Middle East. Local transmission occurred in 13 focal areas in 6 countries in the Americas (Mexico, Guatemala, Ecuador, Colombia, Venezuela, and Brazil), but transmission has now stopped in 11 of these focal areas.
How is river blindness diagnosed? Diagnosis. The gold standard test for the diagnosis of onchocerciasis remains the skin snip biopsy. If a patient has skin nodules caused by onchocercal infection, nodulectomy allows for the identification of macrofilariae (adult worms) in the tissue.
How long does ivermectin last? Ivermectin is metabolized in the liver, and ivermectin and/or its metabolites are excreted almost exclusively in the feces over an estimated 12 days, with less than 1% of the administered dose excreted in the urine. The plasma half-life of ivermectin in man is approximately 18 hours following oral administration.
Which worms can cause blindness? Onchocerciasis, also known as river blindness, is a disease caused by infection with the parasitic worm Onchocerca volvulus. Symptoms include severe itching, bumps under the skin, and blindness. It is the second-most common cause of blindness due to infection, after trachoma.
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